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Saturday, March 17, 2018

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Some bacteria are classified as either Gram positive or Gram negative bacteria.These method was developed by a Danish bacteriologist Hans Christian Joachim Gram noted for his development of Gram stain.The gram staining method is used to differentiate bacteria based on the chemical and physical properties of their cell walls peptidoglycan enabling it to pick up stains.

Both Gram positive and negative bacteria picks up the counter stain however, the counter stain remain unseen on the gram positive bacteria due to the darker crystal violet stain.


Gram positive bacteria 

are those bacteria with a thick layer peptidoglycan present in cell wall.Gram positive bacteria are able to retain the crystal violet dye due to the presence of this thick layer of peptidoglycan and thus stained violet or purple.

Gram negative bacteria

are those bacteria with a thin layer peptidoglycan present in it cell wall.Gram negative bacteria does not pick up primary stain (Crystal violet) after discoloration with alcohol but pick up the counter stain commonly safranin or carbol fuchsine and are stained pink.


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